BDBM50519581 CHEMBL4460916

SMILES COc1ccccc1C(=O)Nc1ccc(cc1C(O)=O)C(=O)c1ccc(cn1)N(C)c1ccc(Cl)cc1

InChI Key InChIKey=LTLCYYDJZIBGJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519581   

TargetLeukotriene C4 synthase(Human)
Orexo

Curated by ChEMBL
LigandPNGBDBM50519581(CHEMBL4460916)
Affinity DataIC50: 35nMAssay Description:Inhibition of human N-terminal His6-tagged LTC4S expressed in Pichia pastoris X33 using LTA4 methyl ester and glutathione as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed