BDBM50519620 CHEMBL4519659

SMILES COc1cc2OCOc2cc1C(CN1CCCC1)c1ccc(cc1)-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(C[C@H](CCN2CCOCC2)CSc2ccccc2)c(c1)S(=O)(=O)C(F)(F)F

InChI Key InChIKey=HYSLRLDMPFHJMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519620   

TargetApoptosis regulator Bcl-2(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50519620(CHEMBL4519659)
Affinity DataIC50: 20nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from human BCl2 expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 2 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed