BDBM50519645 CHEMBL4464023

SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(C)c(CC(=O)OC2CCCCC2)c1

InChI Key InChIKey=WLAXMYKSWGIJKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519645   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519645(CHEMBL4464023)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant RIPK1 (unknown origin) using MBP as substrate preincubated for 15 mins followed by addition of MBP and measured after 120 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519645(CHEMBL4464023)
Affinity DataIC50: 90nMAssay Description:Inhibition of RIP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519645(CHEMBL4464023)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant RIPK3 (unknown origin) using MBP as substrate preincubated for 15 mins followed by addition of MBP and measured after 120 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed