BDBM50519649 CHEMBL4439913

SMILES CNC(=O)c1ccc2n(cnc2c1)-c1ccc(CC(=O)OC(C)(C)C)cc1

InChI Key InChIKey=UGTLDBJIOSYXRR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50519649   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human RIPK1 by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GSK657 binding to human RIPK1 (1 to 328) by fluorescence Polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant RIP3 (2 to 328 residues) expressed in baculovirus by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant RIP3 (2 to 328 residues) expressed in baculovirus by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human RIPK3 (2-328) residues expressed in baculovirus by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human RIPK3 (2-328) residues expressed in baculovirus by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed