BDBM50519940 CHEMBL4476531

SMILES COc1ccc(cc1S(=O)(=O)N(C)c1cc(ccc1N1CCCCC1)C(F)(F)F)C(O)=O

InChI Key InChIKey=NOASDKSTYOVNJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50519940   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of ERAP1 (unknown origin) using WRCYEKMALK as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using WRCYEKMALK as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Mouse)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of recombinant mouse C-terminal His6-tagged IRAP expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519940(CHEMBL4476531)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP2 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using R-AMC as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed