BDBM50519944 CHEMBL4456470

SMILES CC(=O)N1CCN(CC1)C(=O)C1(CCCCC1)NC(=N)Nc1ccc(C)cc1

InChI Key InChIKey=NFVVPTQVHGBUAA-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50519944   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519944(CHEMBL4456470)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519944(CHEMBL4456470)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of ERAP1 in human HeLa cells stably expressing H-2 Kb infected with vaccinia virus containing ss-LEQLE-SIINFEKL epitope assessed as suppre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519944(CHEMBL4456470)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using WRCYEKMALK as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519944(CHEMBL4456470)
Affinity DataKi:  1.28E+4nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed