BDBM50520434 CHEMBL4522946

SMILES C[C@@H]1COCCN1c1nc(nc2sc(nc12)-c1cc[nH]n1)N1CCN(C)CC1

InChI Key InChIKey=LORJBTWECNANDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50520434   

TargetSerine/threonine-protein kinase mTOR(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50520434(CHEMBL4522946)
Affinity DataIC50: 134nMAssay Description:Inhibition of mTOR in mouse MEF cells harboring TSC1 deletion mutant assessed as reduction in PS6 phosphorylation incuabted for 2 hrs alexa fluor 594...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed