BDBM50520810 CHEMBL4547144

SMILES Fc1ccc(cc1)[C@H]1C[C@H](Nc2c1cccc2P(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=IRWNICGRWRYAKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50520810   

TargetDNA topoisomerase 1(Human)
Universidad De Le£N

Curated by ChEMBL
LigandPNGBDBM50520810(CHEMBL4547144)
Affinity DataIC50: 4.22E+4nMAssay Description:Inhibition of human Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed