BDBM50521007 CHEMBL4451935

SMILES CCN(CCCCCCNC(=O)c1cc(O)c(cc1O)C(=O)NCCCCCCN(CC)Cc1ccccc1OC)Cc1ccccc1OC

InChI Key InChIKey=WSJYWRGGMDNKPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521007   

TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed