BDBM50521010 CHEMBL4527242

SMILES CCN(CCCCNC(=O)c1cc(O)c(cc1O)C(=O)NCCCCN(CC)Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=JKEZMFKTWWDUCW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521010   

TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed