BDBM50521246 CHEMBL4526561

SMILES [H][C@]12CSC(N)=N[C@]1(Cc1c(C2)c(Cc2ccc(OC)cc2)cnc1OC)c1ccc(F)cc1F

InChI Key InChIKey=XFIBJZIUSNOOSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521246   

TargetBeta-secretase 2(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50521246(CHEMBL4526561)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using Mca-APP Swedish Lys-Met/Asn-Leu mutant-Dnp quencher as substrate measured at 30 mins interval ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50521246(CHEMBL4526561)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using Mca-APP Swedish Lys-Met/Asn-Leu mutant-Dnp quencher as substrate measured at 30 mins interval ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed