BDBM50521270 CHEMBL4443853

SMILES COc1ccc(F)c(c1)[C@H]1CC[C@H](COc2cccc(c2)[C@@H]([C@H](F)C(O)=O)C2CC2)CC1

InChI Key InChIKey=YURMBFWELBCIAZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521270   

TargetFree fatty acid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521270(CHEMBL4443853)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521270(CHEMBL4443853)
Affinity DataEC50:  163nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed