BDBM50521301 CHEMBL4572575

SMILES Clc1ccc(NC(=O)Nc2ccc(SCc3nc4ccccc4s3)cc2)cc1Cl

InChI Key InChIKey=WIFDASRMFUPXRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521301   

TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521301(CHEMBL4572575)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521301(CHEMBL4572575)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed