BDBM50521330 CHEMBL4450597::US11311528, Ex. 1-76

SMILES CC(C)(C)c1ccc(cc1Cl)N1[C@@H]([C@@H](C(O)=O)c2ccccc2C1=O)c1ccc2SCCSc2c1

InChI Key InChIKey=IKKDTHSQPKJBRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521330   

LigandPNGBDBM50521330(CHEMBL4450597 | US11311528, Ex. 1-76)
Affinity DataIC50: 384nMAssay Description:Displacement of [3H]cGAMP from full length human HAQ STING expressed in Trichopulsia ni membranes preincubated for 30 mins followed by [3H]cGAMP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50521330(CHEMBL4450597 | US11311528, Ex. 1-76)
Affinity DataIC50: 357nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent