BDBM50521441 CHEMBL4475106

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCc1cc(Cc2ccccc2)ccc1O

InChI Key InChIKey=SIBHXJCPROXTFC-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521441   

TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521441(CHEMBL4475106)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521441(CHEMBL4475106)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521441(CHEMBL4475106)
Affinity DataKi:  307nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521441(CHEMBL4475106)
Affinity DataEC50:  552nMAssay Description:Agonist activity at rat Mu-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed