BDBM50521448 CHEMBL4440903

SMILES CCNc1ccc(Cc2ccccc2)cc1CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C

InChI Key InChIKey=ORYHUBULNBLVMQ-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50521448   

TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521448(CHEMBL4440903)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521448(CHEMBL4440903)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521448(CHEMBL4440903)
Affinity DataEC50:  156nMAssay Description:Agonist activity at rat Mu-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521448(CHEMBL4440903)
Affinity DataKi:  408nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50521448(CHEMBL4440903)
Affinity DataEC50: >2.44E+3nMAssay Description:Agonist activity at human kappa-type opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed