BDBM50521470 CHEMBL4462125

SMILES CC1CCn2c(c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c23)C(=O)N1Cc1cccc(c1)C(O)=O

InChI Key InChIKey=NBXQTALFONQFNY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521470   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521470(CHEMBL4462125)
Affinity DataKi:  12nMAssay Description:Inhibition of FITC-labeled Bim peptide binding to His6-tagged MBP-fused Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521470(CHEMBL4462125)
Affinity DataKi: >200nMAssay Description:Inhibition of FITC-labeled Bim peptide binding to His6-tagged MBP-fused Mcl-1 (unknown origin) in presence of 1% fetal bovine serum by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed