BDBM50521737 CHEMBL4457264
SMILES COC(=O)N[C@@H](C(=O)N1[C@@H](C)CC[C@H]1c1ncc([nH]1)-c1cc2COc3cc(cc4COc(c1)c2-c34)-c1cnc([nH]1)[C@@H]1CC[C@H](C)N1C(=O)[C@H](NC(=O)OC)c1ccccc1)c1ccccc1
InChI Key InChIKey=QDWOQNGNTRCYGE-UHFFFAOYSA-N
Data 7 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50521737
Affinity DataEC50: 0.00400nMAssay Description:Inhibition of NS5A in HCV genotype 3a S52 infected in human HuH7 transient chimeric replicon cells assessed as reduction in viral replication after 3...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0150nMAssay Description:Inhibition of NS5A in HCV genotype 4a ED43 infected in human HuH7 transient chimeric replicon cells assessed as reduction in viral replication after ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Inhibition of NS5A in HCV genotype 1b Con1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0940nMAssay Description:Inhibition of NS5A L31M mutant in patient derived HCV genotype 2a MD2b-1 infected in human HuH7 replicon cells assessed as reduction in viral replica...More data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Inhibition of NS5A in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferase...More data for this Ligand-Target Pair
Affinity DataEC50: 1.84nMAssay Description:Inhibition of NS5A L31M mutant in HCV genotype 2a J6 (M31) infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 d...More data for this Ligand-Target Pair