BDBM50521814 CHEMBL4461033

SMILES CCC(CC)CC1(O)CCN(CC1)C(=O)Nc1cc(Oc2ccc(F)cc2)cc(Sc2ccc(cc2)S(C)(=O)=O)c1

InChI Key InChIKey=RGJMOGCHCNBDFX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50521814   

TargetSphingosine 1-phosphate receptor 2(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50521814(CHEMBL4461033)
Affinity DataIC50: 15nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR2 expressed in commercial cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50521814(CHEMBL4461033)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR1 expressed in commercial cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50521814(CHEMBL4461033)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR3 expressed in commercial cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50521814(CHEMBL4461033)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR4 expressed in commercial cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50521814(CHEMBL4461033)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR5 expressed in commercial cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed