BDBM50522002 CHEMBL4531567

SMILES CN1CCN(CC1)c1sc(NC(=O)c2cnn(C3CCC(F)(F)CC3)c2C)nc1C1CCC1

InChI Key InChIKey=BYEBNVUFQRARSV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522002   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50522002(CHEMBL4531567)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Inhibition of human TRPV4 expressed in HEK293 cells assessed as reduction in Ca2+ influx incubated for 30 mins by Fluo4-AM dye basedMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
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