BDBM50522003 CHEMBL4519974

SMILES CN1CCN(CC1)c1sc(NC(=O)c2cnn(c2C)C(C)(C)C)nc1C1CCC1

InChI Key InChIKey=XXMPVCYKUFBEQL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522003   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50522003(CHEMBL4519974)Copy SMILESCopy InChI

Affinity DataIC50: 78nMAssay Description:Inhibition of human TRPV4 expressed in HEK293 cells assessed as reduction in Ca2+ influx incubated for 30 mins by Fluo4-AM dye basedMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL