BDBM50522479 CHEMBL4549483

SMILES COc1ccc2[nH]c(CNc3ccc(cc3)C(N)=N)nc2c1

InChI Key InChIKey=RZADLVZIZRFESU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522479   

TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522479(CHEMBL4549483)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected Sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522479(CHEMBL4549483)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant bovine enterokinase activated N-terminal His-tagged recombinant human KLK1 (19 to 262 residues) expressed in baculovirus in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed