BDBM50522796 CHEMBL4522334

SMILES Nc1nc(N)c2nc(Nc3ccc(F)c(F)c3)ccc2n1

InChI Key InChIKey=CZXKISLXVHXQQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522796   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50522796(CHEMBL4522334)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using 9 uM DHFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed