BDBM50522797 CHEMBL4522888

SMILES Nc1nc(N)c2nc(Nc3cc(F)c(F)c(F)c3)ccc2n1

InChI Key InChIKey=JRPWTASLGZCEKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522797   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50522797(CHEMBL4522888)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using 9 uM DHFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed