BDBM50522803 CHEMBL4469864

SMILES Nc1nc(N)c2nc(Nc3ccc(OC(F)(F)F)cc3)ccc2n1

InChI Key InChIKey=AZYLXOMAQJPRBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522803   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50522803(CHEMBL4469864)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using 9 uM DHFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed