BDBM50523050 CHEMBL4455953

SMILES CC1=C([C@@H](Oc2c1cccc2O)c3ccc(cc3)OCCN4CC(C4)CF)c5cccc(c5)O

InChI Key InChIKey=UEGMBSNOWSMURK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523050   

TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523050(CHEMBL4455953)
Affinity DataIC50: 0.0500nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523050(CHEMBL4455953)
Affinity DataIC50: 0.0500nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)