BDBM50523051 CHEMBL4456532

SMILES CC1=C([C@@H](Oc2c(O)cccc12)c1ccc(OCCN2CC(CF)C2)cc1)c1ccc(F)cc1

InChI Key InChIKey=AIFNNQKPDNXNTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523051   

TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523051(CHEMBL4456532)
Affinity DataIC50: 0.420nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523051(CHEMBL4456532)
Affinity DataIC50: 0.420nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed