BDBM50523293 CHEMBL4439919

SMILES O=C1NC(=O)\C(S1)=C\c1ccc(OCc2cn(nn2)-c2ccccc2)cc1

InChI Key InChIKey=RNPWGOXUYNQYBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523293   

TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523293(CHEMBL4439919)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant COX2 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523293(CHEMBL4439919)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed