BDBM50523337 CHEMBL4452286

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(ccc1=O)-c1ccc2OCOc2c1

InChI Key InChIKey=QZVFUKMYOBSKKZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523337   

TargetCarbonic anhydrase 2(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523337(CHEMBL4452286)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human cytosolic CA 2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523337(CHEMBL4452286)
Affinity DataKi:  28nMAssay Description:Inhibition of membrane bound human CA 9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523337(CHEMBL4452286)
Affinity DataKi:  64nMAssay Description:Inhibition of membrane bound human CA 12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523337(CHEMBL4452286)
Affinity DataKi:  99nMAssay Description:Inhibition of human cytosolic CA 1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed