BDBM50523352 CHEMBL4567068

SMILES CCN1CCN(CC1)c1cnn(-c2ccc(cc2)S(N)(=O)=O)c(=O)c1Cl

InChI Key InChIKey=MIZOVKCXRDKVOZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523352   

TargetCarbonic anhydrase 2(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523352(CHEMBL4567068)
Affinity DataKi:  0.290nMAssay Description:Inhibition of human cytosolic CA 2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523352(CHEMBL4567068)
Affinity DataKi:  0.700nMAssay Description:Inhibition of membrane bound human CA 9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523352(CHEMBL4567068)
Affinity DataKi:  7.20nMAssay Description:Inhibition of membrane bound human CA 12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523352(CHEMBL4567068)
Affinity DataKi:  485nMAssay Description:Inhibition of human cytosolic CA 1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed