BDBM50523471 CHEMBL4443054
SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ncccn2)c1
InChI Key InChIKey=FAUOIWKXVZMERY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50523471
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D4.4 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
Affinity DataEC50: 278nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesce...More data for this Ligand-Target Pair
Affinity DataKi: 318nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataIC50: 463nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Agonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 2.42E+3nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataEC50: 5.58E+3nMAssay Description:Agonist activity at human D3 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesce...More data for this Ligand-Target Pair
Affinity DataKi: 5.99E+3nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataEC50: 8.32E+3nMAssay Description:Agonist activity at human D2L receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesc...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair