BDBM50523480 CHEMBL4587925

SMILES Cc1ccc(nc1)C1CCN(CC(=O)Nc2cccc(C)c2)CC1

InChI Key InChIKey=MGIQZTZYUIHPIO-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50523480   

TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D4.4 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataIC50: 394nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataIC50: 453nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataIC50: 7.11E+4nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523480(CHEMBL4587925)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed