BDBM50523892 CHEMBL4531703

SMILES ONC(=O)[C@H]1CCCC1S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PAVNSONEORCDOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523892   

Target72 kDa type IV collagenase(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50523892(CHEMBL4531703)
Affinity DataIC50: 492nMAssay Description:Inhibition of MMP2 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50523892(CHEMBL4531703)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of MMP9 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed