BDBM50523897 CHEMBL4531635

SMILES ONC(=O)[C@H]1CCCC1S(=O)(=O)c1ccc(NC(=O)OCc2ccccc2)cc1

InChI Key InChIKey=YKYLIBIHPXSXED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523897   

Target72 kDa type IV collagenase(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50523897(CHEMBL4531635)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of MMP2 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50523897(CHEMBL4531635)
Affinity DataIC50: 520nMAssay Description:Inhibition of MMP9 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed