BDBM50523921 CHEMBL4446992

SMILES COc1cc2c(Oc3ccc(cc3F)C3SCC(=O)N3NC(=O)Nc3ccc(F)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=MDXPQQJSGHVAGT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50523921   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of FLT3 (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 352nMAssay Description:Inhibition of c-KIT (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 383nMAssay Description:Inhibition of c-SRC (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 400nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50523921(CHEMBL4446992)
Affinity DataIC50: 6.66E+3nMAssay Description:Inhibition of IGF1R (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed