BDBM50523952 CHEMBL4539203

SMILES [H][C@@]12CN([C@@H](C(=O)NO)[C@]1([H])OC(C)(C)O2)C(=O)c1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=SXAYUKGBGSGLSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523952   

Target72 kDa type IV collagenase(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523952(CHEMBL4539203)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523952(CHEMBL4539203)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523952(CHEMBL4539203)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed