BDBM50523963 CHEMBL4452902

SMILES ONC(=O)[C@H]1CCCN1C(=O)c1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=QRQKVQCDKFEWSW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523963   

TargetNeutrophil collagenase(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523963(CHEMBL4452902)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523963(CHEMBL4452902)
Affinity DataIC50: 503nMAssay Description:Inhibition of human MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523963(CHEMBL4452902)
Affinity DataIC50: 636nMAssay Description:Inhibition of human MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Hamburg

Curated by ChEMBL
LigandPNGBDBM50523963(CHEMBL4452902)
Affinity DataIC50: 731nMAssay Description:Inhibition of human MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed