BDBM50523980 CHEMBL4456753

SMILES CC1(C)OB(OC1(C)C)c1ccc(CC(C#N)c2ccc(cc2)B2OC(C)(C)C(C)(C)O2)cc1

InChI Key InChIKey=MZAAOAJHKMDFEG-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523980   

TargetEstrogen receptor beta(Human)
University of Richmond

Curated by ChEMBL
LigandPNGBDBM50523980(CHEMBL4456753)
Affinity DataEC50:  1.20nMAssay Description:Activation of human ERbeta assessed as induction of transcriptional activation incubated for 24 hrs in presence of 100 uM H2O2 by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Richmond

Curated by ChEMBL
LigandPNGBDBM50523980(CHEMBL4456753)
Affinity DataEC50:  6.10nMAssay Description:Activation of human ERbeta assessed as induction of transcriptional activation incubated for 24 hrs in presence of 50 uM H2O2 by luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Richmond

Curated by ChEMBL
LigandPNGBDBM50523980(CHEMBL4456753)
Affinity DataEC50:  470nMAssay Description:Activation of human ERbeta assessed as induction of transcriptional activation incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed