BDBM50524239 CHEMBL4469780::US12297164, Example 3

SMILES OC(c1ccc(c(F)c1)-c1ccc(NC(=O)Cc2ccc(cc2)[N+]([O-])=O)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=UMANBUHWIZGPIR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524239   

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 1.49E+3nMAssay Description:Inverse agonist activity at Gal4-fused RORgamma LBD (unknown origin) expressed in 293T cells measured after 24 hrs by dual-luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 4.85E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 1.49E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
Go to US Patent