BDBM50524363 CHEMBL4585616

SMILES CC1CCCc2c1nc(N)nc2C1CCCCC1

InChI Key InChIKey=OFMZDKMAXIFZBN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50524363   

TargetHistamine H3 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataEC50:  360nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataEC50:  363nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataIC50: 245nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed