BDBM50524434 CHEMBL4443948

SMILES Clc1nc2ccccc2nc1-c1cn(CC=C)c2ccccc12

InChI Key InChIKey=XKMGPNGFOYHLEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524434   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
University of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50524434(CHEMBL4443948)
Affinity DataIC50: 4.67E+3nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50524434(CHEMBL4443948)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed