BDBM50524456 CHEMBL4444093

SMILES O=C(CN1CCN(CC(=O)Nc2n[nH]c3ncccc23)CC1)Nc1n[nH]c2ncccc12

InChI Key InChIKey=KPEOGOPVKUTIJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524456   

TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50524456(CHEMBL4444093)
Affinity DataIC50: 45nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50524456(CHEMBL4444093)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of self-mediated amyloid beta (1 to 42) (unknown origin) aggregation incubated for 48 hrs by thioflavin-T fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50524456(CHEMBL4444093)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed