BDBM50524513 CHEMBL4520113

SMILES COc1cc(CCC(=O)Nc2cc(ccn2)-c2[nH]c(SC)nc2-c2ccc(F)cc2)cc(OC)c1OC

InChI Key InChIKey=NAXXGCGMDSLZMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524513   

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50524513(CHEMBL4520113)
Affinity DataIC50: 88nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50524513(CHEMBL4520113)
Affinity DataIC50: 363nMAssay Description:Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50524513(CHEMBL4520113)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of human recombinant full length GSK3alpha using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed