BDBM50524527 CHEMBL4455711

SMILES Cc1nc(c([nH]1)-c1ccnc(NC(=O)C2CC2)c1)-c1ccc(F)cc1

InChI Key InChIKey=BHOZITIWJBGALO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524527   

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50524527(CHEMBL4455711)
Affinity DataIC50: 19nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50524527(CHEMBL4455711)
Affinity DataIC50: 53nMAssay Description:Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed