BDBM50524672 CHEMBL4457961

SMILES COc1ccc2CCN(CCC(F)Cc3ccccc3)CCc2c1

InChI Key InChIKey=UORHUEYQEKFSIE-UHFFFAOYSA-N

Data  5 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50524672   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataIC50: 553nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of DOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in CHO-K1 cells membranes after 60 mins by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50524672(CHEMBL4457961)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at MOR (unknown origin) by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed