BDBM50525406 CHEMBL164868

SMILES C[C@@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C

InChI Key InChIKey=RTKIYFITIVXBLE-UHFFFAOYSA-N

Data  10 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50525406   

TargetHistone deacetylase 3(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate measured after 10 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate measured after 30 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate measured after 45 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate measured after 60 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate class 2a measured after 45 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Umr Cnrs 7285

Curated by ChEMBL
LigandPNGBDBM50525406(CHEMBL164868)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human recombinant HDAC9 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed