BDBM50525496 CHEMBL4449189

SMILES Fc1ccc(cc1)C(=O)CSc1nccc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=PSZMYZPRCFMLOG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50525496   

TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 110nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 130nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 130nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 150nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 250nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 260nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525496(CHEMBL4449189)
Affinity DataIC50: 480nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed