BDBM50525888 CHEMBL4460982

SMILES COc1c(ccc2nn(cc12)[C@H](CC(C)C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1ccc(cc1Cl)C(F)(F)F

InChI Key InChIKey=CKMPOAFHGMTZND-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525888   

TargetGlucagon receptor(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50525888(CHEMBL4460982)
Affinity DataKi:  35nMAssay Description:Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed