BDBM50526049 CHEMBL4580396

SMILES Oc1cc(-c2ncc(o2)-c2ccc(Oc3ccccc3)cc2)c(Br)c(Br)c1O

InChI Key InChIKey=KIXMILGBYMZQTC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526049   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of TCPTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PTP1B A27S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 7.78E+3nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50526049(CHEMBL4580396)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed