BDBM50526154 CHEMBL4460191

SMILES CC(CNC(=O)Nc1ccc(cc1)C(C)(C)C)CN(C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=PFYPVZCYAJWGGR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50526154   

TargetHistone-arginine methyltransferase CARM1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50526154(CHEMBL4460191)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50526154(CHEMBL4460191)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50526154(CHEMBL4460191)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EHMT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50526154(CHEMBL4460191)
Affinity DataIC50: 100nMAssay Description:Inhibition of DOT1L in human THP1 cells assessed as reduction in H3K79 methylation measured after 7 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50526154(CHEMBL4460191)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed